The stock has more than doubled over the last month as the company began publishing efficacy data. Can Senate Handle Trump’s Impeachment And A New Stimulus Package At Once? • In Singapore, the Expert Committee on Immunisation (ECI) recommends the HPV vaccination for females aged nine to 26 years old. [Updated 11/11/2020] Why Pfizer’s Vaccine Data Is Good News For Moderna. | Takeda. Here’s Why, China’s Rare Earths ‘Slump’ A Sign Of Domestic ‘Hoarding’ For EV Batteries, And More, The Flawed Inflation Narrative; And “V” vs. “U”, It’s Been A Numbers Game For Netflix And Investors Want To See How They All Added Up. The Southeast Asian carrier is in talks with some of the vaccine manufacturers, and working out details of the planned trials, according to The … Takeda Vaccines Pte. Prime Minister Jacinda Ardern has said upon approval, the first batches will be delivered to frontline workers and essential staff by the second quarter of 2021. While Moderna’s stock trades at about $150 per share, its valuation still looks reasonable at about 25x our projected 2020 EPS. For example, not all viruses are similar to Covid, which mRNA might be better at mimicking. Other areas? , Moderna is working with multiple partners to produce its vaccine. Called Lunar-Cov19, the vaccine is developed by Duke-NUS Medical School and American pharmaceutical company Arcturus Therapeutics. Unlike traditional vaccines which use a virus protein that needs to be grown over the course of weeks, mRNA molecules – which instruct the body to produce virus proteins by itself – are less complex and are produced via a chemical process (rather than a biological process) making mass production much quicker. [Updated 11/10/2020] What Does Pfizer’s Vaccine Readout Mean For Its Stock?Pfizer (NYSE: PFE) and its German partner BioNTech indicated that their Coronavirus vaccine, dubbed BNT162b2, was over 90% effective at preventing Covid-19 infections among volunteers, based on early data from phase 3 trials. You may opt-out by. While the company doesn’t have any other products on the market yet, its flu vaccine NanoFlu could be ready for potential FDA approval. (related: How Will The Covid-19 Vaccine Impact Moderna’s EPS?) SINGAPORE - The Republic is building up its vaccine-manufacturing capacity even as researchers around the world race to develop one for Covid … 6. The Pfizer-BioNTech vaccine is expected to approved by Australian regulators by the end of January, Morrison said. In a recent poll by NHK, 36% of respondents didn't want to take a Covid-19 vaccine. Moderna (MRNA) , a clinical-stage biotech company, is carrying out phase 3 trials of its Covid-19 vaccine, completing enrollment of 30,000 participants. For perspective, the Covid-19 vaccine was apparently designed within a few days. Most other countries are still waiting on local regulators to approve vaccine candidates before they can roll out inoculation programs -- and in the meantime, are scrambling to sign deals with pharmaceutical companies to buy the coveted doses in advance. With enough doses secured for 44 million people, the government is aiming to vaccinate 80% of its population. Moderna’s vaccine will also be more expensive than rivals, as it is likely to cost between $25 and $37 per dose, depending on the volume of the order, compared to about $19 per dose for the Pzifer vaccine.  Lonza is also producing the vaccine in the U.S. at its New Hampshire facility. Two shots of the vaccine will be required per person. [Updated 11/17/2020] What The Covid Vaccine Means For Moderna Stock, On Monday, Moderna (NASDAQ: MRNA) stock rallied by over 10% after the company said that its Covid-19 vaccine – which is based on messenger RNA technology – was 94.5% effective based on preliminary data. (Related: Are Covid Vaccine Stocks Worth Investing In?) The country is also working to secure deals with American companies. The stock is up 253% this year. Arcturus (Nasdaq: ARCT) hopes the compound will prove effective as a vaccine against SARS-CoV-2, the virus that causes COVID-19. Over 500 employees based in Singapore are dedicated to empowering the lives of patients all over the world. This is also the age range recommended by most of the manufacturers and for which the vaccines are approved for use in Singapore by the Health Sciences Authority. SINGAPORE has made arrangements with various pharmaceutical companies to facilitate their clinical trials and drug development in Singapore, with the government having attracted a few players to establish vaccine manufacturing capabilities here. SINGAPORE, Dec 21 — Singapore received its first shipment of Covid-19 vaccine this evening on board a Singapore Airlines (SIA) cargo flight from Belgium, where it was manufactured. Chan, however, did not … Chinese Premier Li Keqiang said some Southeast Asian countries would be given priority, including Cambodia, Laos, Myanmar, Thailand and Vietnam. CAMBRIDGE, Mass.--(BUSINESS WIRE)--Dec. 14, 2020-- Moderna, Inc., (Nasdaq: MRNA) a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients, today confirmed that the Company concluded an agreement with the Ministry of Health of Singapore to supply mRNA-1273, Moderna’s vaccine … Novartis provides healthcare solutions that improve and extend people’s lives. On top of this, vaccine manufacturers are required to … This is positive news, considering that Moderna has no real manufacturing track record and has never produced or sold a commercial drug prior to the Covid-19 shot. Some would … We maintain strict product-quality standards and multiple supply-chain safeguards to ensure the efficacy, safety and supply of our products - no matter where our medicines and vaccines are manufactured. While messenger RNA (mRNA) based vaccines were touted to be more potent and quicker to deploy compared to traditional vaccines, they have never been used commercially to date. India has authorized two Covid-19 vaccines for use, putting its enormous vaccine-manufacturing capacity in the spotlight. Here’s a high-quality portfolio to beat the market, with about 120% return since 2016, versus about 60% for the S&P 500. Singapore: The first batch of volunteers aged between 21 and 55 in Singapore have received a dose of a potential coronavirus vaccine being developed in the country. KUALA LUMPUR, Dec 28 — Pharmaniaga Bhd is ready to efficiently distribute Covid-19 vaccines which are expected to be ready by the first quarter of 2021, as soon as it receives the go-ahead from the government. While most vaccine stocks declined last week, amid a broader sell-off in the markets, they are likely to come back into the spotlight as efficacy data from late-stage trials is expected from frontrunners Pfizer (NYSE: PFE) and Moderna (NASDAQ: MRNA) in the coming weeks. mRNA offers significant flexibility with vaccine and potentially drug development. That said, Moderna’s success with Covid doesn’t guarantee that its vaccines and therapeutics in other areas, such as cancer, will be as effective. There is a lot of competition in the race for a Covid-19 vaccine, and it’s likely that there will be multiple successful candidates from other companies. Gan added that vaccine recipients will also be observed on-site for 30 minutes after receiving their vaccination, so that any severe allergic reactions such as anaphylaxis can be detected and promptly treated. Johnson & Johnson (JNJ): Unlike most other vaccine candidates, which are likely to require two shots, J&J is targeting a single-dose vaccine. Now the initial data from Pfizer and its German partner BioNtech’s Covid-19 vaccine appears to confirm this, with the vaccine’s efficacy standing at 90% based on initial data, versus the U.S. FDA’s baseline efficacy requirement of just 50% for the approval for Covid-19 vaccines. Data sources: Biotechnology Innovation Organizati… For instance, even Pfizer, which also uses mRNA technology and has an established manufacturing base, had to halve its initial vaccine production target for this year to 50 million doses due to some supply chain constraints. While there is a possibility that the efficacy rate of Pfizer’s vaccine could change as more data comes in, the numbers are no doubt encouraging. Comprised of companies with strong revenue growth, healthy profits, lots of cash, and low risk, it has outperformed the broader market year after year, consistently. Investors cheered the news, sending Moderna stock up by about 20% on Monday’s trading. ), More importantly for Moderna investors, the vaccine’s results also bode well for the rest of the company’s pipeline, which is entirely based on mRNA technology which has never been used previously in commercial drugs. Both governments have said the vaccines will be free and voluntary for citizens. By the end of March, four million people should have been vaccinated, according to Prime Minister Scott Morrison. The company is likely to have data on whether its vaccine works or not by this month, and has noted that it would seek emergency approval from the FDA if the vaccine is at least 70% effective. [11/27/2020] What’s Happening With Moderna Stock?Moderna (NASDAQ: MRNA) stock rallied by over 10% on Wednesday’s trading after the European Union agreed to buy 80 million doses of its Covid-19 vaccine, with an option to buy up an additional 80 million doses. Several companies already had vaccine platforms targeting other coronaviruses such as MERS and SARS. (related: A Look At Moderna’s Pipeline Beyond The Covid Vaccine). While there are two other vaccines by drug majors Pfizer and AstraZeneca that have reported phase 3 results, it looks like Moderna’s vaccine offers the best balance of efficacy and ease of storage and distribution. The two vaccines: The Serum Institute of India (SII) has been manufacturing the vaccine developed by Oxford University and AstraZeneca. Australia expects to start administering the first dose in mid-to-late February to priority groups, including quarantine and border workers, frontline healthcare workers, and residents in aged and disability care. Following are all of the companies that are actively developing COVID-19 vaccines either on their own or in partnership with another drugmaker. The company also said that it was continuing to invest and add staff to potentially produce as much as 1 billion doses for the full year. Although the number could change as more data comes in, it is nevertheless indicative of a highly effective vaccine. Also, vaccines traditionally have lower profitability versus prescription drugs. NDAQ While the company had to pause trials in mid-October after an illness was reported in a volunteer, the company is now preparing to resume trials. STRONG MANUFACTURING PRESENCE IN SINGAPORE. The theme is up by about 877% year-to-date versus about 14% for the S&P 500. The country also secured deals with AstraZeneca and Novavax to secure 50 million doses from each company, but no details were released on when the shipments will arrive. The companies are on track to file an emergency use application with the U.S. FDA later this month if pending data indicates that the vaccine is safe. in the U.S., and by ROVI and Recipharm outside the U.S. See our indicative theme of Covid-19 Vaccine stocks which includes U.S.-listed pharma and biotech companies. That being said, some hiccups are to be expected as the company works with a tight timeline. So how is the company going to meet demand? Competition is also likely to mount as there are likely to be several more successful vaccine candidates from other companies in the coming quarters. The country is still evaluating other candidates, including China's. Combined with the large public interest in facilitating vaccine access, these margins may face even more downward pressure. The vaccine will be free of charge, with a goal to vaccinate 50 million people ahead of February's Lunar New Year celebrations.  The companies intend to manufacture up to 50 million doses this year, and as much as 1.3 billion doses in 2021. SII is allowed to produce the Oxford-AstraZeneca vaccine for use within India, but the government has barred them for export until at least March or April -- meaning other countries may have to source their Oxford-AstraZeneca doses from other production sites.  The speed and the efficacy of the Covid vaccine also indicate that Moderna could leverage this technology to develop new lines of vaccines against a variety of viruses. A coolroom at Singapore's Changi Airport, preparing for the arrival of its first shipment of Pfizer-BioNTech vaccines, on December 16, 2020.  Moderna’s vaccine offers an efficacy that’s similar to Pfizer’s and can apparently be stored at refrigerator-like temperatures for 30 days. mRNA-based Covid vaccines focused on the novel coronavirus’ spike protein – which is on the outside of the virus – but there are other viruses whose harmful regions are hidden, making it more difficult for mRNA to address. Sanofi is another of the top vaccine manufacturers in the world specialized in research and … Pharmaniaga is ready to efficiently distribute Covid-19 vaccines as soon as it receives the go-ahead from the government. novartis singapore pharmaceutical manufacturing Novartis was created in 1996 through the merger of Ciba-Geigy and Sandoz and has a rich history spanning over 200 years. Once a large percentage of the global population is vaccinated (likely by 2022 or 2023) the earnings potential of the Covid vaccine will diminish. . Firstly, supply will remain an issue in the near-term. The theme is up by about 721 % year-to-date versus about 13% for the S&P 500. Surprisingly, the founders of Trefis discovered that along with most other people they just did not understand even the seemingly familiar companies around them: Apple, Google, Coca Cola, Walmart, GE, Ford, Gap, and others. No Choosing Of Vaccines. Japanese Prime Minister Yoshihide Suga at a press conference in Tokyo on January 4. [Updated 11/4/2020] Covid-19 Vaccine stocks. There are still some concerns though. The vaccine was over 94% effective in preventing Covid-19 and 100% effective in preventing severe cases of infection – meaning that no one who received the vaccine developed a serve case of the infection. As well as global, regional and local commercial operations, we have a significant manufacturing presence in Singapore, comprising two global manufacturing supply sites and a vaccines manufacturing facility. Some countries like the United States and United Kingdom have already begun vaccinating priority groups and the public. While the EPS impact of the Covid-19 vaccine could be fleeting, the validation of Moderna’s messenger RNA (mRNA) technology could be far more consequential for investors. the background on Christmas Eve. Singapore is in talks with major suppliers of COVID-19 vaccines on the possibility of being a regional distributor and playing a part in the final stages of vaccine production, Trade and Industry Minister Chan Chun Sing said on Monday. You can play with assumptions, or try scenarios, as-well-as ask questions to other users and experts. Opinions expressed by Forbes Contributors are their own. Germany’s CordenPharma will produce the lipids – which are used to deliver the mRNA. The strong efficacy and the speed at which the vaccine was developed should essentially reduce the perceived risk surrounding the rest of Moderna’s pipeline of 21 vaccines and therapies for rare diseases. Separately, Swiss regulators have reportedly allowed Moderna’s contract manufacturer Lonza Group to start producing its Covid-19 vaccine at a plant in Switzerland, which will apparently have a capacity to produce 800,000 doses a day. Large parts of the rich … Moderna’s Covid-19 vaccine could emerge as the most sought-after vaccine, particularly in developed markets – considering the high levels of efficacy as well as manageable refrigeration requirements, unlike Pfizer’s candidate which is also highly effective but needs to be stored at ultra-cold temperatures. Meanwhile, Russia has signed agreements with four Indian manufacturers to produce about 300 million doses of the Russian-developed Sputnik V vaccine, according to Russian, China approved its first homegrown coronavirus vaccine for general public use. For example, clinical-stage biotech Moderna (NASDAQ: MRNA), which also uses an mRNA-based technology like the Pfizer vaccine, is slated to report efficacy data in the coming weeks. The results are surprisingly strong, considering that the U.S. FDA had set a baseline efficacy of just 50% for the approval for Covid-19 vaccines. Updated 0231 GMT (1031 HKT) January 9, 2021. A health official prepares a vaccine kit during a Covid-19 vaccine mock drill in Chennai on January 2. AstraZeneca’s vaccine, on the other hand, faces concerns regarding some gaps in its trial data, which could undermine its reported results. Using a lower-dose first shot, which conserves the vaccine, and then a full-dose second shot provided protection about 90% of the time, the company and university found. As we’ve said before, Moderna’s Covid-19 vaccine is likely to emerge as the most sought-after vaccine in developed markets, considering its stellar efficacy rates and relative ease of storage. While Moderna intends to produce between 500 million to 1 billion doses of its vaccine over 2021, it has no real manufacturing track record and has never produced or sold a commercial drug to date. All Rights Reserved, This is a BETA experience. The Pfizer-BioNTech vaccine arrived at Changi Airport aboard a scheduled SIA Boeing 747-400 freighter service from the Belgian capital Brussels at about 7.35pm. The company is likely to have efficacy data from late-stage trials available shortly. (Photo illustration by Artur Widak/NurPhoto via Getty Images). Singapore is the regional headquarters of our Emerging Markets and Asia Pacific pharmaceutical and consumer healthcare businesses. Read more at The Business Times. The theme is up about 3x over the last 2 years. Firstly, the efficacy compares favorably with Pfizer’s Covid vaccine, which reported efficacy of 90%. While Moderna has a Covid vaccine of its own in the works, with efficacy data expected any time now, the strong response of Pfizer’s mRNA bodes well not just for Moderna’s Covid efforts, but also for the rest of the company’s sizable pipeline which is focused mostly on vaccines and therapies for rare diseases. Considering that the vaccine is co-developed with BioNTech, any profits will likely be shared. Elderly citizens, health care workers, and those with chronic illness will be first in line to receive a free dose when the initial batch of a million Sinovac doses arrives in January. MSD manufactures medicines and vaccines that are sold in more than 140 countries. Moderna’s Cytomegalovirus (CMV) vaccine, which is currently in phase 2 studies and could move to phase 3 in 2021, is likely to be the company’s first candidate for approval after its Covid-19 vaccine. The Oxford-AstraZeneca vaccine could be approved in February. Once the vaccine is produced, the fill-finish operation – which is the process of filling vials and packaging the vaccine for distribution – is handled by Catalent That’s below the S&P 500 that trades at about 26x projected earnings. Investors have good reason to be optimistic about Moderna for multiple reasons. However, there are a couple of factors that could help the company scale up quickly. The company has 21 programs underway, around 13 of which are in the clinical stage. Is this jump warranted? Secondly, Moderna’s vaccine should be easier to distribute compared to Pfizer’s, as it can likely be stored at refrigerator-like temperatures for 30 days, unlike Pfizer’s vaccine which requires much colder temperatures of around -94 degrees Fahrenheit – limiting its use to more developed parts of the world. [Updated 12/1/2020]Moderna (NASDAQ The country will also receive 2 million doses of the Sinovac vaccine in three batches, delivered in February, March and April. The companies are on track to file an emergency use application with the U.S. FDA later this month if pending data indicates that the vaccine is safe. Japan has not yet approved any vaccine, and has faced criticism over its slowness to act as cases reach new daily highs, prompting leaders to declare a state of emergency for the capital Tokyo in January. What if you’re looking for a more balanced portfolio instead? 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